Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881815 | 0.90 | HPGD (0.46) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL21881520 | 0.90 | HPGD (0.46) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL10047780 | 0.89 | PTPN1 (0.42) | AGTR2PTPN1PTGER4PTGER3PTGER2 | |
| SCHEMBL18608232 | 0.89 | AGTR2 (0.59) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL21881848 | 0.89 | AGTR2 (0.59) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL21881185 | 0.89 | AGTR2 (0.59) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| Hydrochloric Acid SCHEMBL29758892 | 0.88 | AGTR2 (0.58) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| Hydrochloric Acid SCHEMBL21596260 | 0.88 | AGTR2 (0.58) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL23315467 | 0.80 | AGTR2 (0.49) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 | |
| SCHEMBL21881614 | 0.80 | AGTR2 (0.49) | KDM4ECYP1A2CYP2D6CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021445-B2 | Carboxylic acid derivative as AT2R receptor antagonist | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-06-01 | — | — | US | disclosed |
| US-20200102275-A1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102275-A1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | AGTR2, AGTR1, HCAR2 | KDM4E 4199/4885CYP1A2 863/4885CYP2D6 873/4885 |
| US-11021445-B2 | Carboxylic acid derivative as AT2R receptor antagonist | AGTR2, AGTR1, HCAR2 | KDM4E 4199/4885CYP1A2 863/4885CYP2D6 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.