Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225965 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9645840 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL235094 | 0.88 | MGAM (0.48) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL4075525 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL3046232 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL2959866 | 0.84 | MGAM (0.44) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL15187255 | 0.82 | MGAM (0.43) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL28070845 | 0.82 | TSHR (0.36) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL28262928 | 0.82 | MGAM (0.43) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL15187221 | 0.82 | MGAM (0.43) | ALDH1A1TRPA1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340482-B | Synthesis method of brivaracetam | 四川诺非特生物药业科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-115340510-B | Preparation method of brivaracetam intermediate | 天津辰欣药物研究有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-115340482-A | Synthesis method of brivaracetam | 四川诺非特生物药业科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115340510-A | Preparation method of brivaracetam intermediate | 天津辰欣药物研究有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114989061-A | Preparation method of brivaracetam | 江苏同禾药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111675643-B | Preparation method of brivaracetam | 浙江天宇药业股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-111675643-A | Preparation method of brivaracetam | 浙江天宇药业股份有限公司 | 2020-09-18 | — | — | CN | disclosed |
| WO-2020051796-A1 | PREPARATION METHOD FOR BRIVARACETAM AND INTERMEDIATE THEREOF | 上海宣泰医药科技有限公司 | 2020-03-19 | — | — | WO | disclosed |
| WO-2020052545-A1 | METHOD FOR PREPARING BRIVARACETAM AND INTERMEDIATES THEREOF | 上海宣泰医药科技有限公司 | 2020-03-19 | — | — | WO | disclosed |
| CN-108503573-B | A kind of new preparation method of Bu Waxitan | 北京艾百诺医药股份有限公司 | 2019-11-22 | — | — | CN | disclosed |
| CN-108689903-A | A kind of new preparation method of Bu Waxitan | 北京艾百诺医药股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108503573-A | A kind of new preparation method of Bu Waxitan | 北京艾百诺医药股份有限公司 | 2018-09-07 | — | — | CN | disclosed |