Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070844 | 1.00 | TSHR (0.36) | TSHRZDHHC7CA1CA2CA12 | |
| SCHEMBL13506382 | 0.87 | TSHR (0.42) | TSHRZDHHC7CA1CA2CA12 | |
| SCHEMBL11356150 | 0.87 | TSHR (0.42) | TSHRZDHHC7CA1CA2CA12 | |
| SCHEMBL26802498 | 0.83 | CA2 (0.39) | TSHRZDHHC7CA1CA2CA12 | |
| SCHEMBL21881999 | 0.82 | ALDH1A1 (0.48) | TSHRCA1CA2CA12HSD17B10 | |
| SCHEMBL20225965 | 0.82 | ALDH1A1 (0.48) | TSHRCA1CA2CA12HSD17B10 | |
| SCHEMBL28228511 | 0.82 | TSHR (0.37) | TSHRZDHHC7CA1CA2CA12 | |
| SCHEMBL21801003 | 0.80 | TSHR (0.38) | TSHRCA1CA2CA12CA14 | |
| SCHEMBL21801004 | 0.80 | TSHR (0.38) | TSHRCA1CA2CA12CA14 | |
| SCHEMBL21052370 | 0.80 | TSHR (0.46) | TSHRCA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126092-A | Preparation method of brivaracetam | 上海上药创新医药技术有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-105646319-B | A kind of preparation method of Bu Waxitan | 佛山市隆信医药科技有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-105646319-A | Preparation method of brivaracetam | 佛山市隆信医药科技有限公司 | 2016-06-08 | — | — | CN | disclosed |