Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL299882 | 1.00 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1459186 | 0.98 | NPC1 (0.36) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL299327 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Iodide SCHEMBL299417 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Iodide SCHEMBL2186162 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28000315 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| N,N-Dimethylethanaminium SCHEMBL446053 | 0.83 | NPC1 (0.40) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL21743 | 0.82 | NPC1 (0.42) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| N,N-Dimethylethanaminium SCHEMBL7062326 | 0.81 | NPC1 (0.39) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Acrylic Acid SCHEMBL28857978 | 0.81 | ALOX15 (0.39) | NPC1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10036239-B2 | Graphene enhanced polymer composites and methods thereof | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-07-31 | — | — | US | claimed |
| US-20160340570-A1 | GRAPHENE ENHANCED POLYMER COMPOSITES AND METHODS THEREOF | HALLIBURTON ENERGY SERVICES INC. | 2016-11-24 | — | — | US | claimed |
| US-7182136-B2 | Methods of reducing water permeability for acidizing a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. (US) | 2007-02-27 | — | — | US | claimed |
| US-20070012444-A1 | Apparatus and method for reducing water production from a hydrocarbon producing well | HALLIBURTON ENERGY SERVICES, INC. | 2007-01-18 | — | — | US | claimed |
| US-7114568-B2 | Hydrophobically modified polymers for a well completion spacer fluid | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-10-03 | — | — | US | claimed |
| US-20050230114-A1 | Hydrophobically modified polymers for a well completion spacer fluid | HALLIBURTON ENERGY SERVICES, INC. | 2005-10-20 | — | — | US | claimed |
| US-20050178549-A1 | Methods of reducing the permeabilities of horizontal well bore sections | HALLIBURTON ENERGY SERVICES, INC. | 2005-08-18 | — | — | US | claimed |
| WO-2005003515-A1 | METHODS OF REDUCING WATER PERMEABILITY FOR ACIDIZING A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2005-01-13 | — | — | WO | claimed |
| US-20050000694-A1 | Methods of reducing water permeability for acidizing a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. | 2005-01-06 | — | — | US | claimed |
| US-6476169-B1 | Methods of reducing subterranean formation water permeability | HALLIBURTON ENERGY SERVICES, INC. | 2002-11-05 | — | — | US | claimed |
| EP-1193365-A1 | Reducing subterranean formation water permeability | Halliburton Energy Services, Inc. (US) | 2002-04-03 | — | — | EP | claimed |
| US-20230416598-A1 | ACIDIZING COMPOSITIONS FOR IMPROVED FLUID PERFORMANCE | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-12-28 | — | — | US | disclosed |
| US-11787999-B2 | Acidizing compositions for improved fluid performance | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| WO-2021133414-A1 | ACIDIZING COMPOSITIONS FOR IMPROVED FLUID PERFORMANCE | HALLIBURTON ENERGY SERVICES, INC. (US) | 2021-07-01 | — | — | WO | disclosed |
| US-20210198560-A1 | Acidizing Compositions for Improved Fluid Performance | HALLIBURTON ENERGY SERVICES, INC. (US) | 2021-07-01 | — | — | US | disclosed |
| US-20050178549-A1 | Methods of reducing the permeabilities of horizontal well bore sections | HALLIBURTON ENERGY SERVICES, INC. | 2005-08-18 | — | — | US | disclosed |
| WO-2005003515-A1 | METHODS OF REDUCING WATER PERMEABILITY FOR ACIDIZING A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050000694-A1 | Methods of reducing water permeability for acidizing a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004101706-A1 | METHOD FOR STIMULATING HYDROCARBON PRODUCTION AND REDUCING THE PRODUCTION OF WATER FROM A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| US-20040229756-A1 | Method for stimulating hydrocarbon production and reducing the production of water from a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. | 2004-11-18 | — | — | US | disclosed |