Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2186162 | 1.00 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1459186 | 0.98 | NPC1 (0.36) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL299327 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL299882 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL2188209 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28000315 | 0.97 | NPC1 (0.35) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| N,N-Dimethylethanaminium SCHEMBL446053 | 0.83 | NPC1 (0.40) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Trimethylammonium SCHEMBL21743 | 0.82 | NPC1 (0.42) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| N,N-Dimethylethanaminium SCHEMBL7062326 | 0.81 | NPC1 (0.39) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| Acrylic Acid SCHEMBL28857978 | 0.81 | ALOX15 (0.39) | NPC1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598631-B2 | Sulfonated relative permeability modifiers for reducing subterranean formation water permeability | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-03-21 | — | — | US | claimed |
| US-20170002262-A1 | SULFONATED RELATIVE PERMEABILITY MODIFIERS FOR REDUCING SUBTERRANEAN FORMATION WATER PERMEABILITY | HALIBURTON ENERGY SERVICES, INC. (US) | 2017-01-05 | — | — | US | claimed |
| EP-2009076-A1 | Method for stimulating hydrocarbon production and reducing the production of water from a subterranean formation | Halliburton Energy Services, Inc. (US) | 2008-12-31 | — | — | EP | claimed |
| EP-1644458-A1 | METHOD FOR STIMULATING HYDROCARBON PRODUCTION AND REDUCING THE PRODUCTION OF WATER FROM A SUBTERRANEAN FORMATION | Halliburton Energy Services, Inc. (US) | 2006-04-12 | — | — | EP | claimed |
| WO-2004101706-A1 | METHOD FOR STIMULATING HYDROCARBON PRODUCTION AND REDUCING THE PRODUCTION OF WATER FROM A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2004-11-25 | — | — | WO | claimed |
| US-20040229756-A1 | Method for stimulating hydrocarbon production and reducing the production of water from a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. | 2004-11-18 | — | — | US | claimed |
| US-11248167-B2 | Acid diversion in naturally fractured formations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| EP-3556989-A1 | THROUGH TUBING BRIDGE PLUG AND INSTALLATION METHOD FOR SAME | Halliburton Energy Services, Inc. (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-2483517-B1 | ANCHOR ASSEMBLY AND METHOD FOR ANCHORING A DOWNHOLE TOOL | HALLIBURTON ENERGY SERVICES INC (US) | 2019-05-15 | — | — | EP | disclosed |
| US-10024132-B2 | Through tubing bridge plug and installation method for same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| WO-2018004624-A1 | ACID DIVERSION IN NATURALLY FRACTURED FORMATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-01-04 | — | — | WO | disclosed |
| US-9759046-B2 | Pipe-in-pipe shunt tube assembly | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| EP-2877684-B1 | PIPE-IN-PIPE SHUNT TUBE ASSEMBLY | HALLIBURTON ENERGY SERVICES INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-20100051271-A1 | Sand Control Screen Assembly and Method For Use of Same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| WO-2010025150-A2 | SAND CONTROL SCREEN ASSEMBLY AND METHOD FOR USE OF SAME | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010025155-A1 | SAND CONTROL SCREEN ASSEMBLY AND METHOD FOR USE OF SAME | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20100051262-A1 | Sand Control Screen Assembly and Method for Use of Same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2009076-A1 | Method for stimulating hydrocarbon production and reducing the production of water from a subterranean formation | Halliburton Energy Services, Inc. (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20070012444-A1 | Apparatus and method for reducing water production from a hydrocarbon producing well | HALLIBURTON ENERGY SERVICES, INC. | 2007-01-18 | — | — | US | disclosed |
| EP-1193365-A1 | Reducing subterranean formation water permeability | Halliburton Energy Services, Inc. (US) | 2002-04-03 | — | — | EP | disclosed |