Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116658 | 0.84 | TGFBR1 (0.33) | TGFBR1SCN5ASCN9A | |
| SCHEMBL21882310 | 0.81 | CSF1R (0.34) | TGFBR1SCN5ASCN9A | |
| SCHEMBL27116692 | 0.78 | MTOR (0.33) | TGFBR1 | |
| SCHEMBL27116638 | 0.78 | NCF1 (0.32) | — | |
| SCHEMBL21882349 | 0.77 | TGFBR1 (0.38) | TGFBR1SCN5ASCN9A | |
| SCHEMBL21425572 | 0.76 | CSF1R (0.35) | TGFBR1SCN5ASCN9A | |
| SCHEMBL27116610 | 0.74 | CSF1R (0.33) | TGFBR1SCN5ASCN9A | |
| SCHEMBL21882307 | 0.74 | CSF1R (0.32) | TGFBR1SCN5ASCN9A | |
| SCHEMBL21882287 | 0.72 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL21882309 | 0.71 | CSF1R (0.36) | TGFBR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-A1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |