Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ATF4 | P18848 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21819430 | 0.92 | ATF4 (0.50) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL21882069 | 0.84 | ATF4 (0.57) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL27865005 | 0.83 | RAB9A (0.52) | L3MBTL1NPC1RAB9ABCAT1KDM4E | |
| Hydrochloric Acid SCHEMBL27726072 | 0.82 | RAB9A (0.51) | L3MBTL1NPC1RAB9ABCAT1KDM4E | |
| SCHEMBL24998177 | 0.82 | ATF4 (0.55) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL29988250 | 0.82 | ATF4 (0.55) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL30578702 | 0.81 | ATF4 (0.57) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL23920291 | 0.81 | ATF4 (0.57) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL21819462 | 0.80 | ATF4 (0.63) | L3MBTL1ATF4NPC1RAB9AHRH4 | |
| SCHEMBL22777693 | 0.80 | ATF4 (0.56) | L3MBTL1ATF4NPC1RAB9AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166942-B2 | Inhibitors of integrated stress response pathway | Praxis Biotech LLC (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200101047-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | Praxis Biotech LLC | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166942-B2 | Inhibitors of integrated stress response pathway | ATF4, DDIT3, ATF1 | L3MBTL1 1975/4885ATF4 1/4885NPC1 2384/4885 |
| US-20200101047-A1 | INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY | ATF4, DDIT3, ATF1 | L3MBTL1 1975/4885ATF4 1/4885NPC1 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.