Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27726072 | 0.99 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL21882370 | 0.83 | L3MBTL1 (0.55) | RAB9ANPC1KMT2AKDM4EHSD17B10 | |
| SCHEMBL16825864 | 0.79 | MAPT (0.76) | RAB9ANPC1SMN1; SMN2MAPTPOLB | |
| Trifluoroacetic Acid SCHEMBL21819430 | 0.77 | ATF4 (0.50) | RAB9ANPC1KDM4EHSD17B10L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28581487 | 0.76 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| Piperazine SCHEMBL28827893 | 0.75 | FLT3 (0.61) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| Hydrochloric Acid SCHEMBL9343546 | 0.75 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL7041640 | 0.75 | MAPT (0.53) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL5592854 | 0.73 | TP53 (0.69) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL28891069 | 0.73 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102267985-A | Preparation method for vilazodone and hydrochloride thereof | — | 2011-12-07 | — | — | CN | disclosed |