Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27421239 | 0.87 | HCAR2 (0.47) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL27421238 | 0.87 | HCAR2 (0.47) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL5974442 | 0.86 | HCAR2 (0.46) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL5974445 | 0.86 | HCAR2 (0.46) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL5974441 | 0.86 | HCAR2 (0.46) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL17560760 | 0.78 | PAM (0.51) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL21937369 | 0.76 | MEN1 (0.64) | HDAC3HDAC2HDAC8KMT2AMEN1 | |
| SCHEMBL7594903 | 0.76 | MEN1 (0.64) | HDAC3HDAC2HDAC8KMT2AMEN1 | |
| SCHEMBL19449623 | 0.76 | MEN1 (0.64) | HDAC3HDAC2HDAC8KMT2AMEN1 | |
| SCHEMBL3445449 | 0.76 | SMN1; SMN2 (0.64) | CA1CA2CA4CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | HCAR2 2875/4885CA12 1497/4885AKR1B10 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.