Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951516 | 0.82 | ALOX12 (0.40) | UTS2RCYP19A1ALOX12NPSR1LMNA | |
| SCHEMBL21820653 | 0.75 | SLC6A9 (0.47) | UTS2RALOX12MDM2NPSR1LMNA | |
| SCHEMBL28757336 | 0.75 | ALOX12 (0.47) | CYP19A1ALOX12NPSR1LMNAHTT | |
| SCHEMBL12086639 | 0.73 | ALOX12 (0.55) | ALOX12NPSR1LMNAHTTL3MBTL1 | |
| SCHEMBL27973945 | 0.72 | ALOX12 (0.47) | ALOX12NPSR1LMNAHTTL3MBTL1 | |
| SCHEMBL13253341 | 0.72 | NPSR1 (0.46) | UTS2RNPSR1LMNAHTTL3MBTL1 | |
| SCHEMBL11931775 | 0.71 | NPSR1 (0.43) | UTS2RNPSR1LMNAHTTL3MBTL1 | |
| SCHEMBL10924034 | 0.71 | UTS2R (0.55) | UTS2RCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9379783 | 0.70 | MAPT (0.45) | UTS2RALOX12MDM2LMNAHTT | |
| SCHEMBL11931714 | 0.69 | HTT (0.47) | UTS2RNPSR1LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | UTS2R 3741/4885CYP19A1 482/4885ALOX12 2596/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | UTS2R 3741/4885CYP19A1 482/4885ALOX12 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.