Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496460 | 1.00 | ADORA2A (0.44) | ADORA2AALKBH1TUBB4ATUBBTUBA3C | |
| SCHEMBL21883519 | 0.86 | ALKBH1 (0.44) | ADORA2AALKBH1TUBB4ATUBBTUBA3C | |
| SCHEMBL30020902 | 0.86 | ALKBH1 (0.44) | ADORA2AALKBH1TUBB4ATUBBTUBA3C | |
| SCHEMBL21883964 | 0.83 | SMN1; SMN2 (0.41) | ADORA2AALKBH1HPGDALDH1A1ADORA3 | |
| SCHEMBL30496441 | 0.83 | SMN1; SMN2 (0.41) | ADORA2AALKBH1HPGDALDH1A1ADORA3 | |
| SCHEMBL21883963 | 0.83 | DAPK1 (0.44) | ADORA2AALKBH1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL30496472 | 0.83 | DAPK1 (0.44) | ADORA2AALKBH1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL23322497 | 0.83 | ALKBH1 (0.40) | ADORA2AALKBH1HPGDADORA3ADORA1 | |
| SCHEMBL30496470 | 0.83 | ALKBH1 (0.40) | ADORA2AALKBH1HPGDADORA3ADORA1 | |
| SCHEMBL17025300 | 0.82 | UCHL1 (0.43) | ALKBH1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112673008-B | Hypoxanthine compounds | 橘生药品工业株式会社 | 2023-07-18 | — | — | CN | disclosed |
| US-20210214357-A1 | HYPOXANTHINE COMPOUNDS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-07-15 | — | — | US | disclosed |
| EP-3819299-A1 | HYPOXANTHINE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-05-12 | — | — | EP | disclosed |
| CN-112673008-A | Hypoxanthine compound | 橘生药品工业株式会社 | 2021-04-16 | — | — | CN | disclosed |
| WO-2020054825-A1 | HYPOXANTHINE COMPOUND | キッセイ薬品工業株式会社 | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214357-A1 | HYPOXANTHINE COMPOUNDS | HPRT1, DHPS, PAH | ADORA2A 2291/4885ALKBH1 89/4885TUBB4A 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.