Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | ADA | P00813 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974098 | 0.81 | NR1I2 (0.47) | NR1I2SLC2A1GPR84ADA | |
| SCHEMBL3040111 | 0.74 | NR1I2 (0.39) | NR1I2 | |
| SCHEMBL174988 | 0.74 | NR1I2 (0.39) | NR1I2SLC2A1GPR84ADA | |
| SCHEMBL28275300 | 0.74 | NR1I2 (0.55) | NR1I2SLC2A1 | |
| SCHEMBL20098162 | 0.74 | NR1I2 (0.55) | NR1I2SLC2A1 | |
| SCHEMBL18948424 | 0.73 | NR1I2 (0.40) | NR1I2SLC2A1GPR84ADA | |
| SCHEMBL25150378 | 0.73 | UHRF1 (0.38) | NR1I2SLC2A1GPR84ADA | |
| Hydrochloric Acid SCHEMBL29252979 | 0.72 | NR1I2 (0.54) | NR1I2SLC2A1 | |
| SCHEMBL19003601 | 0.72 | NR1I2 (0.53) | NR1I2 | |
| SCHEMBL22458264 | 0.72 | NR1I2 (0.37) | NR1I2SLC2A1GPR84ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | NR1I2 2629/4885SLC2A1 566/4885LTB4R 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.