SCHEMBL25150378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18879378	0.85	KDM4E (0.38)	UHRF1NR1I2PSEN1PSEN2APH1B
	SCHEMBL174988	0.85	NR1I2 (0.39)	NR1I2SLC2A1KDM4EHPGDGPR84
	SCHEMBL22298879	0.83	UHRF1 (0.38)	UHRF1NR1I2PSEN1PSEN2APH1B
	SCHEMBL22260475	0.82	NR1I2 (0.37)	NR1I2SLC2A1KDM4EHPGDGPR84
	SCHEMBL22458264	0.82	NR1I2 (0.37)	NR1I2SLC2A1KDM4EHPGDGPR84
	SCHEMBL3443825	0.82	AR (0.38)	NR1I2SLC2A1KDM4EHPGDGPR84
	SCHEMBL3443064	0.82	NOS3 (0.43)	NR1I2SLC2A1KDM4EGPR84ADA
	SCHEMBL18672331	0.81	NOS3 (0.42)	NR1I2SLC2A1KDM4EGPR84ADA
	SCHEMBL27345654	0.81	KCNH2 (0.42)	NR1I2SLC2A1KDM4EGPR84
	SCHEMBL19185480	0.81	NOS3 (0.42)	NR1I2SLC2A1KDM4EGPR84ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.