Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 2/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974098 | 0.93 | NR1I2 (0.47) | NR1I2SLC2A1GPR84CCR1CCR5 | |
| SCHEMBL175672 | 0.93 | CCR1 (0.38) | NR1I2SLC2A1GPR84CCR1CCR5 | |
| Bromide SCHEMBL2514869 | 0.90 | CCR1 (0.35) | CCR1CCR5CCR8KDM5ABDKRB2 | |
| SCHEMBL145233 | 0.87 | CCR1 (0.33) | CCR1CCR5CCR8BDKRB2 | |
| SCHEMBL3040111 | 0.86 | NR1I2 (0.39) | NR1I2CCR1CCR5CCR8KDM5A | |
| Chloromethane SCHEMBL6909514 | 0.85 | CYP1A2 (0.38) | CCR1CCR5CCR8KDM4E | |
| SCHEMBL25150378 | 0.85 | UHRF1 (0.38) | NR1I2SLC2A1GPR84ADABDKRB2 | |
| SCHEMBL5973792 | 0.85 | GPR84 (0.38) | NR1I2SLC2A1GPR84CCR1CCR5 | |
| SCHEMBL13039644 | 0.85 | LNPEP (0.37) | KDM4E | |
| SCHEMBL22458264 | 0.83 | NR1I2 (0.37) | NR1I2SLC2A1GPR84ADABDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-03-08 | — | — | US | disclosed |
| US-7825199-B1 | mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft | CARNEGIE MELLON UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| EP-2147042-A1 | DENDRITIC MOLECULES | The University Of Queensland (AU) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008141357-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | CD40LG, CD40, TLR3 | NR1I2 4212/4885SLC2A1 4655/4885GPR84 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.