SCHEMBL5974098

SCHEMBL5974098

CCCCCCC(CC)c1ccnc(-c2cc(C(CC)CCCCCC)ccn2)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.47
SLC2A1 P11166 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
KDM5A P29375 1/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
ADA P00813 2/20 0.33
TBXAS1 P24557 1/20 0.32
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
BDKRB2 P30411 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3040111 0.93 NR1I2 (0.39) NR1I2KDM5ACCR1CCR5CCR8
SCHEMBL174988 0.93 NR1I2 (0.39) NR1I2SLC2A1GPR84KDM5ACCR1
SCHEMBL175672 0.86 CCR1 (0.38) NR1I2SLC2A1GPR84KDM5ACCR1
Bromide SCHEMBL2514869 0.83 CCR1 (0.35) KDM5ACCR1CCR5CCR8BDKRB2
SCHEMBL11396126 0.82 CCR1 (0.43) KDM5ACCR1CCR5CCR8KDM4E
SCHEMBL5973792 0.82 GPR84 (0.38) NR1I2SLC2A1GPR84KDM5ACCR1
SCHEMBL21883566 0.81 NR1I2 (0.42) NR1I2SLC2A1GPR84ADA
SCHEMBL145233 0.81 CCR1 (0.33) CCR1CCR5CCR8BDKRB2
SCHEMBL5495738 0.80 GPR84 (0.36) NR1I2SLC2A1GPR84KDM5ACCR1
Chloromethane SCHEMBL6909514 0.80 CYP1A2 (0.38) CCR1CCR5CCR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966489-B1 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION UNIV CARNEGIE MELLON (US) 2006-11-15 EP disclosed