Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 3/20 | 0.37 |
| ▸ | LDHB | P07195 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13563242 | 0.85 | F2RL1 (0.36) | LDHALDHBF2RL1HPGDKDM4E | |
| SCHEMBL19880547 | 0.83 | NOS3 (0.35) | NOS2PTGS1PTGS2ALDH1A1CYP3A4 | |
| SCHEMBL2047097 | 0.83 | NOS2 (0.44) | NOS2LDHALDHBHPGDKDM4E | |
| SCHEMBL135071 | 0.82 | ALDH1A1 (0.40) | PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL19115415 | 0.79 | F2RL1 (0.42) | NOS2CXCR5F2RL1HPGDKDM4E | |
| SCHEMBL5681133 | 0.79 | NOS2 (0.41) | NOS2LDHALDHBHPGDESR1 | |
| SCHEMBL23387415 | 0.78 | PRKCI (0.46) | NOS2LDHALDHBPTGS2HPGD | |
| SCHEMBL23491275 | 0.78 | HPGD (0.44) | PTGS1PTGS2HPGDKDM4EALDH1A1 | |
| SCHEMBL28700541 | 0.76 | NOS2 (0.39) | NOS2LDHALDHBHPGDKDM4E | |
| SCHEMBL20076488 | 0.75 | NOS2 (0.37) | NOS2CXCR5F2RL1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | NOS2 1227/4885LDHA 3305/4885LDHB 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.