SCHEMBL21883773

SCHEMBL21883773

Cc1cc(OCCO[Si](C)(C)C(C)(C)C)cc(C)c1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
DUT P33316 2/20 0.34
PDIA6 Q15084 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MCL1 Q07820 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5467419 0.83 RAB9A (0.43) DUTPDIA6CA12CA1CA2
SCHEMBL29502883 0.83 RAB9A (0.43) DUTPDIA6CA12CA1CA2
SCHEMBL618157 0.81 TP53 (0.38) POLBDUTCA12CA1CA2
SCHEMBL5469399 0.80 ALDH1A1 (0.41) DUTPDIA6CA12CA1CA2
SCHEMBL4737246 0.77 MAPT (0.44) POLBDUTPDIA6CA12CA1
SCHEMBL27083521 0.77 KDM4E (0.36) DUTCA12CA1CA2CA9
SCHEMBL31201071 0.77 ALOX5AP (0.37) DUTCA12CA1CA2CA9
SCHEMBL15814847 0.77 TDP1 (0.47) DUTCA12CA1CA2CA9
SCHEMBL9934160 0.76 ALDH1A1 (0.37) DUTPDIA6ALDH1A1TP53CYP3A4
SCHEMBL8472793 0.75 TSHR (0.53) ALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020071798-A1 COMPOUND, COLORED RESIN COMPOSITION, COLOR FILTER, AND DISPLAY DEVICE 동우 화인켐 주식회사 2020-04-09 WO disclosed