Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502883 | 0.85 | RAB9A (0.43) | MAPTSMN1; SMN2TSHRPDIA6MEN1 | |
| SCHEMBL5467419 | 0.85 | RAB9A (0.43) | MAPTSMN1; SMN2TSHRPDIA6MEN1 | |
| SCHEMBL3362279 | 0.84 | NSD2 (0.41) | MAPTKDM4EALDH1A1DUTCA12 | |
| SCHEMBL30221972 | 0.81 | DUT (0.34) | PDIA6KDM4EALDH1A1DUTCA12 | |
| SCHEMBL20521475 | 0.81 | DUT (0.34) | PDIA6KDM4EALDH1A1DUTCA12 | |
| SCHEMBL13196947 | 0.81 | KDM4E (0.42) | MAPTSMN1; SMN2MAPK1LMNAMEN1 | |
| SCHEMBL2474081 | 0.80 | ALDH1A1 (0.54) | MAPTSMN1; SMN2MAPK1LMNATSHR | |
| SCHEMBL5469399 | 0.79 | ALDH1A1 (0.41) | MAPTSMN1; SMN2PDIA6MEN1KMT2A | |
| SCHEMBL3690504 | 0.79 | CA12 (0.47) | MAPTSMN1; SMN2MAPK1LMNAALOX15 | |
| SCHEMBL15831460 | 0.78 | DRD2 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075955-A2 | PROCESS FOR THE PREPARATION OF 1,4,5-TRISUBSTITUTED TRIAZOLES AND 3,4,5-TRISUBSTITUTED TRIAZOLES | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2008-06-26 | — | — | WO | disclosed |