⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21922075 | 0.72 | CSNK1A1 (0.40) | — | |
| SCHEMBL19782065 | 0.67 | CSNK1A1 (0.34) | — | |
| SCHEMBL29768800 | 0.67 | CSNK1A1 (0.36) | — | |
| SCHEMBL18125583 | 0.64 | CYP11B2 (0.45) | — | |
| SCHEMBL19779692 | 0.64 | TSHR (0.37) | — | |
| SCHEMBL22096833 | 0.60 | CYP11B1 (0.32) | — | |
| SCHEMBL19779742 | 0.60 | CYP2E1 (0.37) | — | |
| SCHEMBL27294895 | 0.60 | KDM4E (0.46) | — | |
| SCHEMBL19768943 | 0.60 | KDM5A (0.36) | — | |
| SCHEMBL1256303 | 0.58 | PRKCZ (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |