Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Quinuclidinone SCHEMBL1900903 | 0.91 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| Methylene Quinuclidinone SCHEMBL6857718 | 0.89 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| Methylene Quinuclidinone SCHEMBL2229287 | 0.89 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KDM4EMAPK1MAPT | |
| SCHEMBL10631548 | 0.67 | ENO1 (0.34) | ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL5016631 | 0.61 | — | — | |
| SCHEMBL18309422 | 0.61 | CHRM3 (0.33) | — | |
| SCHEMBL6461385 | 0.59 | DAO (0.33) | MAPT | |
| SCHEMBL21335045 | 0.58 | DAO (0.39) | ALDH1A1MAPTGAA | |
| SCHEMBL14032991 | 0.57 | CHRNB2 (0.37) | — | |
| SCHEMBL3182637 | 0.55 | DAO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020058458-A1 | QUINUCLIDINE-3-ONE DERIVATIVES AND THEIR USE IN CANCER TREATMENT | APREA THERAPEUTICS AB (SE) | 2020-03-26 | — | — | WO | disclosed |