Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884585 | 0.86 | XDH (0.41) | XDHMAOB | |
| SCHEMBL24066321 | 0.80 | XDH (0.52) | XDHMAOBFOLH1MRGPRX4 | |
| SCHEMBL1534077 | 0.78 | XDH (0.55) | XDHMAOBFOLH1MRGPRX4 | |
| SCHEMBL23874972 | 0.78 | XDH (0.55) | XDHMAOBFOLH1MRGPRX4 | |
| SCHEMBL23874985 | 0.77 | XDH (0.52) | XDHMAOBFOLH1MRGPRX4 | |
| SCHEMBL21884509 | 0.77 | XDH (0.60) | XDHMAOB | |
| SCHEMBL5026568 | 0.72 | XDH (0.71) | XDHMAOBMRGPRX4 | |
| SCHEMBL21884652 | 0.71 | MAOB (0.48) | XDHMAOB | |
| SCHEMBL23875025 | 0.70 | XDH (0.53) | XDHMRGPRX4 | |
| SCHEMBL6817642 | 0.70 | MRGPRX4 (0.50) | XDHMAOBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |