Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884584 | 0.86 | XDH (0.49) | XDHMAOB | |
| SCHEMBL21884506 | 0.82 | XDH (0.47) | XDHMAOB | |
| SCHEMBL21884589 | 0.81 | XDH (0.46) | XDHMAOBPTPN1 | |
| SCHEMBL21884495 | 0.80 | XDH (0.47) | XDHMAOBPTPN1 | |
| SCHEMBL23875124 | 0.72 | XDH (0.45) | XDH | |
| SCHEMBL23875065 | 0.72 | XDH (0.43) | XDHMAOB | |
| SCHEMBL6660069 | 0.71 | MAPT (0.47) | PTPN1 | |
| SCHEMBL23413759 | 0.70 | MAOB (0.53) | MAOB | |
| SCHEMBL1534077 | 0.70 | XDH (0.55) | XDHMAOB | |
| SCHEMBL23414364 | 0.69 | TDP1 (0.45) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |