Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024877 | 0.88 | XDH (0.60) | XDHALDH1A1MAOB | |
| SCHEMBL20897567 | 0.87 | MRGPRX4 (0.64) | XDHALDH1A1HPGDMRGPRX4NR4A2 | |
| SCHEMBL1749528 | 0.84 | RXRA (0.62) | XDHHPGD | |
| SCHEMBL1329717 | 0.83 | XDH (0.55) | XDHMAOB | |
| SCHEMBL28587139 | 0.83 | XDH (0.55) | XDHMAOB | |
| Hydrochloric Acid SCHEMBL28326093 | 0.82 | F2 (0.56) | XDHMAOB | |
| SCHEMBL1600077 | 0.82 | MRGPRX4 (0.62) | HPGDMRGPRX4NR4A2 | |
| SCHEMBL29556736 | 0.82 | MRGPRX4 (0.62) | HPGDMRGPRX4NR4A2 | |
| SCHEMBL8319025 | 0.81 | PTGER1 (0.67) | XDHALDH1A1HPGDMRGPRX4NR4A2 | |
| SCHEMBL1402221 | 0.81 | ALDH1A1 (0.74) | XDHALDH1A1HPGDMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092072-A2 | MODULATORS OF THE METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 5 AND USES THEREOF | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-07-31 | — | — | WO | disclosed |