Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.41 |
| ▸ | MET | P08581 | 8/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884830 | 0.91 | KDR (0.56) | KDRPDGFRBKMT2AMEN1SRC | |
| SCHEMBL21884883 | 0.91 | KDR (0.56) | KDRPDGFRBKMT2AMEN1SRC | |
| SCHEMBL21884878 | 0.83 | KDR (0.49) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL30365337 | 0.79 | KDR (0.58) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL30365200 | 0.79 | KDR (0.58) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL21884825 | 0.79 | KDR (0.58) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL21884860 | 0.79 | KDR (0.58) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL21884863 | 0.77 | KDR (0.62) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL21886117 | 0.77 | KDR (0.58) | KDRPDGFRBSRCTGFBR1MET | |
| SCHEMBL30365379 | 0.77 | KDR (0.58) | KDRPDGFRBSRCTGFBR1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |