Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 5/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | FER | P16591 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884878 | 0.92 | KDR (0.49) | HSD17B10KDRPDGFRBMETFLT3 | |
| SCHEMBL21884833 | 0.91 | KDR (0.56) | HSD17B10KDRPDGFRBMETFLT3 | |
| SCHEMBL21884865 | 0.82 | KDR (0.57) | KDRPDGFRBMETFLT3AXL | |
| SCHEMBL21886108 | 0.81 | KDR (0.56) | KDRPDGFRBMETFLT3AXL | |
| SCHEMBL21884880 | 0.81 | KDR (0.52) | HSD17B10KDRPDGFRBMETFLT3 | |
| SCHEMBL21886116 | 0.81 | KDR (0.52) | HSD17B10KDRPDGFRBMETFLT3 | |
| SCHEMBL21885576 | 0.81 | KDR (0.52) | HSD17B10KDRPDGFRBMETFLT3 | |
| SCHEMBL30365234 | 0.81 | KDR (0.52) | HSD17B10KDRPDGFRBMETFLT3 | |
| SCHEMBL21886115 | 0.79 | KDR (0.52) | KDRPDGFRBMETFLT3AXL | |
| SCHEMBL21884866 | 0.79 | KDR (0.52) | KDRPDGFRBMETFLT3AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |