SCHEMBL21885247

SCHEMBL21885247

c1ccc(-c2ccc(-c3ccc(N(c4ccc(-c5cccc6ccccc56)cc4)c4ccc(-c5cccc6c5c5ccccc5n5c7ccccc7c(-c7ccccc7)c65)cc4)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
PPARG P37231 8/20 0.34
PPARA Q07869 8/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
PPARD Q03181 1/20 0.34
MCL1 Q07820 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
TNF P01375 1/20 0.32
FLT3 P36888 1/20 0.32
BMX P51813 1/20 0.32
CYP1A2 P05177 1/20 0.31
PDE6D O43924 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21885244 0.99 PPARG (0.34) CA12CA1CA2CA9PPARG
SCHEMBL21885246 0.94 MAPK14 (0.30)
SCHEMBL21885040 0.93
SCHEMBL21885253 0.88 CA12 (0.34) CA12CA1CA2CA9PPARG
SCHEMBL21885255 0.87 CA12 (0.39) CA12CA1CA2CA9PPARG
SCHEMBL21885052 0.87 CA12 (0.39) CA12CA1CA2CA9PPARG
SCHEMBL21885311 0.87 CA12 (0.39) CA12CA1CA2CA9PPARG
SCHEMBL21885268 0.86 PPARG (0.34) CA12CA1CA2CA9PPARG
SCHEMBL21885322 0.86
SCHEMBL21885758 0.84 MAPK14 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE MAOA, PNMT, TPH1 CA12 4649/4885CA1 4127/4885CA2 4503/4885
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device MAOA, PNMT, TPH1 CA12 4649/4885CA1 4127/4885CA2 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.