SCHEMBL218856

SCHEMBL218856

C=C(C)C(=O)NCCNC(=O)CC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 2/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
ADRA1A P35348 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219655 0.92 MEN1 (0.40) TGFBR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL316224 0.86 TGFBR1 (0.41) TGFBR1ALDH1A1KDM4EMAPK1HIF1A
SCHEMBL4453310 0.83 MEN1 (0.43) ALDH1A1MEN1KMT2AKDM4EKDM6B
SCHEMBL9148100 0.83 ALDH1A1 (0.48) TGFBR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL16267884 0.79 TGFBR1 (0.38) TGFBR1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL11866190 0.79 TGFBR1 (0.38) TGFBR1ALDH1A1KDM4EMAPK1HIF1A
SCHEMBL2612361 0.79 KDM4E (0.50) TGFBR1ALDH1A1KDM4EADRA1ALMNA
SCHEMBL16384922 0.79 EPHX1 (0.39) TGFBR1ALDH1A1KDM4EMAPK1HIF1A
SCHEMBL8426209 0.78 FAAH (0.42) TGFBR1ALDH1A1
SCHEMBL112305 0.77 TGFBR1 (0.36) TGFBR1ALDH1A1KDM4EMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684473-B1 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions JOHNSON & JOHNSON CLIN DIAG (US) 2001-11-07 EP claimed
US-5739230-A CURABLE THROUGH A MICHAEL REACTION BETWEEN A COMPONENT HAVING A PLURALITY OF ALPHA,BETA-UNSATURATED CARBONYL GROUPS AND A COMPONENT HAVING A PLURALITY OF ACTIVATED METHYLENE GROUPS NIPPON PAINT CO., LTD. (JP) 1998-04-14 US claimed
US-5696193-A WATER SOLUBLE POLYMER; SPREADING LAYER ON IMMUNOASSAYANALYTICAL ELEMENT CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) 1997-12-09 US claimed
US-5622997-A SURFACE MODIFYING BP CHEMICALS LIMITED 1997-04-22 US claimed
EP-0684473-A2 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions Johnson & Johnson Clinical Diagnostics, Inc. (US) 1995-11-29 EP claimed
US-5066376-A Crosslinked Acrylamide Type Gel Medium EASTMAN KODAK COMPANY (US) 1991-11-19 US claimed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP claimed
EP-0273679-A2 Improved method for effecting enzymatic reactions and an enzymatic reactor useful therein EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-07-06 EP claimed
US-4247673-A COLOR COUPLERS, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1981-01-27 US claimed
US-4215195-A CROSSLINKABLE, POLYMERIC COLOR COUPLERS, GELATIN EXTENDERS, BINDERS EASTMAN KODAK COMPANY (US) 1980-07-29 US claimed
WO-2023213742-A1 COATING COMPOSITION AND PREPARATION FOR THE SAME BASF SE (DE) 2023-11-09 WO disclosed
CN-107418281-B Putty composition and repair coating method using same 关西涂料株式会社 2021-08-03 CN disclosed
US-20200369809-A1 AN ADDITIVE COMPOSITION AND APPLICATION THEREOF BASF ADVANCED CHEMICALS CO., LTD. (CN) 2020-11-26 US disclosed
WO-2019101556-A1 AN ADDITIVE COMPOSITION AND APPLICATION THEREOF BASF SE (DE) 2019-05-31 WO disclosed
EP-1539832-B2 SELF-CROSSLINKABLE WATERBORNE COATING COMPOSITION VALSPAR SOURCING INC (US) 2014-08-06 EP disclosed
US-4358524-A Polymeric vehicle for metallizable dye image-receiving layer EASTMAN KODAK COMPANY (US) 1982-11-09 US disclosed
US-4346231-A Polymerizable ethylenically unsaturated amide compounds PONTICELLO IGNAZIO S 1982-08-24 US disclosed
US-4247673-A COLOR COUPLERS, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4215195-A CROSSLINKABLE, POLYMERIC COLOR COUPLERS, GELATIN EXTENDERS, BINDERS EASTMAN KODAK COMPANY (US) 1980-07-29 US disclosed
EP-0013147-A2 POLYMERISABLE MONOMERS, THEIR USE TO PREPARE CROSS-LINKABLE POLYMERS AND THE CROSS-LINKABLE POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-07-09 EP disclosed