Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | RBP4 | P02753 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23203185 | 0.83 | BRD4 (0.49) | BACE1RBP4L3MBTL3L3MBTL1POLB | |
| SCHEMBL28942169 | 0.81 | RBP4 (0.50) | RBP4MEN1KMT2APOLBBRD4 | |
| SCHEMBL2636989 | 0.80 | RBP4 (0.52) | RBP4MEN1KMT2AL3MBTL1BRD4 | |
| SCHEMBL19926965 | 0.80 | RBP4 (0.52) | RBP4MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL27900121 | 0.80 | TRPV1 (0.55) | RBP4MEN1KMT2APOLBBRD4 | |
| SCHEMBL4675402 | 0.80 | RBP4 (0.52) | RBP4MEN1KMT2APOLBBRD4 | |
| SCHEMBL2636181 | 0.80 | RBP4 (0.49) | RBP4MEN1KMT2ATP53RAB9A | |
| SCHEMBL21885670 | 0.78 | GPR119 (0.55) | MEN1KMT2APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL30436742 | 0.78 | GPR119 (0.55) | MEN1KMT2APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL2101664 | 0.78 | RBP4 (0.47) | RBP4MEN1KMT2APOLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784655-B1 | PROCESS FOR PREPARING 2-(1-(TERT-BUTOXYCARBONYL)PIPERIDINE-4-YL)BENZOIC ACID | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3784655-A1 | PROCESS FOR PREPARING 2-(1-(TERT-BUTOXYCARBONYL)PIPERIDINE-4-YL)BENZOIC ACID | Theravance Biopharma R&D IP, LLC (US) | 2021-03-03 | — | — | EP | disclosed |
| US-10640467-B2 | Process for preparing 2-(1-(tert-butoxycarbonyl)piperidine-4-yl)benzoic acid | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2020-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640467-B2 | Process for preparing 2-(1-(tert-butoxycarbonyl)piperidine-4-yl)benzoic acid | BDNF, GABRE, NPY5R | BACE1 515/4885RBP4 3103/4885MEN1 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.