Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.34 |
| ▸ | ABAT | P80404 | 3/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2601956 | 0.78 | KDM4E (0.46) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL4371754 | 0.75 | KDM4E (0.59) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL30225085 | 0.75 | KDM4E (0.59) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL4367756 | 0.73 | KDM4E (0.42) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL4339392 | 0.73 | ALDH1A1 (0.44) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL25371194 | 0.73 | ALDH1A1 (0.57) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL4769958 | 0.73 | ALDH1A3 (0.43) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL13644405 | 0.73 | ALDH1A1 (0.43) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL13644404 | 0.73 | ALDH1A1 (0.43) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL29955595 | 0.73 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1ALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632908-A1 | INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF CANCER | Inventiva (FR) | 2020-04-08 | — | — | EP | disclosed |