Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541492 | 0.80 | SRD5A1 (0.47) | SMN1; SMN2CYP2D6CYP2C9ATAD2BMPR1B | |
| SCHEMBL1119387 | 0.78 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BSMN1; SMN2CYP2D6 | |
| SCHEMBL19910573 | 0.78 | SMN1; SMN2 (0.40) | HTR2AHTR2CSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL5541484 | 0.78 | SMN1; SMN2 (0.43) | TRIM24SMN1; SMN2CYP2D6CYP2C9ATAD2 | |
| SCHEMBL8126458 | 0.78 | ATAD2 (0.59) | SMN1; SMN2CYP2D6CYP2C9ATAD2BMPR1B | |
| SCHEMBL25318142 | 0.78 | CYP2D6 (0.42) | SMN1; SMN2CYP2D6CYP2C9ATAD2BMPR1B | |
| SCHEMBL29896920 | 0.78 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BSMN1; SMN2CYP2D6 | |
| SCHEMBL19910561 | 0.77 | TP53 (0.42) | SMN1; SMN2CYP2D6CYP2C9ATAD2BMPR1B | |
| SCHEMBL6608548 | 0.76 | SRD5A1 (0.49) | TRIM24SMN1; SMN2DRD2MAPTCYP1A2 | |
| SCHEMBL5956393 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2D6CYP2C9DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115341-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115341-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | TRIM24 2744/4885HTR2A 2145/4885HTR2C 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.