Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25987132 | 0.90 | PDE4B (0.40) | GPR119 | |
| SCHEMBL30988791 | 0.87 | GPR119 (0.37) | GPR119ALKKCNH2 | |
| SCHEMBL30988767 | 0.83 | GPR119 (0.37) | GPR119ALK | |
| SCHEMBL21886828 | 0.83 | GPR119 (0.37) | GPR119ALK | |
| SCHEMBL28560474 | 0.83 | GPR119 (0.37) | GPR119ALK | |
| SCHEMBL21886629 | 0.81 | HRH3 (0.32) | — | |
| SCHEMBL17630410 | 0.77 | TBK1 (0.44) | GPR119 | |
| SCHEMBL17630409 | 0.77 | TBK1 (0.44) | GPR119 | |
| SCHEMBL20934896 | 0.76 | GPR119 (0.40) | GPR119 | |
| SCHEMBL20934757 | 0.76 | GPR119 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057511-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | SUZHOU ZANRONG PHARMA LIMITED (CN) | 2020-03-26 | — | — | WO | disclosed |