Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19181080 | 0.76 | TYMP (0.52) | MAPK1HPGDTK1DUTTYMP | |
| SCHEMBL19181341 | 0.74 | TOP2A (0.40) | MAPK1TOP2AHPGDTK1DUT | |
| SCHEMBL9353739 | 0.73 | DUT (0.64) | MAPK1TOP2AHPGDTK1DUT | |
| SCHEMBL3025206 | 0.72 | MAPK1 (0.46) | MAPK1HPGDTK1ALDH1A1NPSR1 | |
| SCHEMBL9353951 | 0.71 | TYMP (0.42) | MAPK1TOP2AHPGDTK1DUT | |
| SCHEMBL9354252 | 0.71 | DUT (0.55) | MAPK1HPGDTK1DUTTYMP | |
| SCHEMBL17274630 | 0.71 | TYMP (0.54) | MAPK1HPGDTK1ALDH1A1NPSR1 | |
| SCHEMBL6703360 | 0.70 | MAPK1 (0.45) | MAPK1HPGDTK1ALDH1A1NPSR1 | |
| SCHEMBL9357958 | 0.70 | TYMP (0.44) | MAPK1TOP2AHPGDTK1DUT | |
| SCHEMBL19995056 | 0.69 | MAPK1 (0.44) | MAPK1HPGDTK1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072991-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |