Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703360 | 0.78 | MAPK1 (0.45) | MAPK1HPGDALDH1A1NPSR1TYMP | |
| SCHEMBL19995056 | 0.77 | MAPK1 (0.44) | MAPK1HPGDALDH1A1NPSR1TYMP | |
| SCHEMBL2635616 | 0.76 | MAPK1 (0.42) | MAPK1HPGDALDH1A1NPSR1TYMP | |
| SCHEMBL4342113 | 0.74 | TYMP (0.49) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL8910349 | 0.74 | MAPK1 (0.41) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL6911384 | 0.73 | TYMP (0.44) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL13724687 | 0.72 | MAPK1 (0.43) | MAPK1HPGDTYMPTK1LMNA | |
| SCHEMBL21886851 | 0.72 | MAPK1 (0.40) | MAPK1HPGDALDH1A1NPSR1TYMP | |
| SCHEMBL11257611 | 0.72 | TK1 (0.49) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL7832846 | 0.72 | MAPK1 (0.43) | MAPK1HPGDALDH1A1NPSR1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196273-A1 | NOVEL AGENT FOR IN VIVO PET IMAGING OF TUMOR PROLIFERATION | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2010-08-05 | — | — | US | disclosed |
| WO-2008100848-A2 | NOVEL AGENT FOR IN VIVO PET IMAGING OF TUMOR PROLIFERATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-08-21 | — | — | WO | disclosed |