Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808034 | 0.81 | ALDH1A1 (0.44) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL28114068 | 0.80 | HPGD (0.41) | PDE3AKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL2416172 | 0.76 | ALDH1A1 (0.58) | PDE3AKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL9929711 | 0.76 | MEN1 (0.42) | PDE3AKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL27926958 | 0.69 | ALDH1A1 (0.64) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL23087507 | 0.69 | PDE3A (0.43) | PDE3AKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL31431229 | 0.69 | MAPT (0.59) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL14150626 | 0.69 | TRPV4 (0.53) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL23948615 | 0.68 | MEN1 (0.41) | PDE3AKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL31503799 | 0.67 | KDM4E (0.44) | KDM4EMAPTHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057511-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | SUZHOU ZANRONG PHARMA LIMITED (CN) | 2020-03-26 | — | — | WO | disclosed |