SCHEMBL21887202

SCHEMBL21887202

O=C(O)C1=CC(=O)c2cc(C(=O)O)ccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 3/20 0.58
▸ PTPRC P08575 2/20 0.56
▸ KMT2A Q03164 4/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ MAPT P10636 3/20 0.47
▸ TDP1 Q9NUW8 3/20 0.47
▸ L3MBTL1 Q9Y468 3/20 0.47
▸ CDC25B P30305 2/20 0.47
▸ HPGD P15428 1/20 0.47
▸ CDC25A P30304 1/20 0.47
▸ CTDSP1 Q9GZU7 1/20 0.47
▸ MAP2K7 O14733 1/20 0.46
▸ CSNK2A2 P19784 6/20 0.45
▸ CSNK2B P67870 6/20 0.45
▸ CSNK2A1 P68400 6/20 0.45
▸ CSNK2A3 Q8NEV1 6/20 0.45
▸ POLB P06746 4/20 0.45
▸ ALDH1A1 P00352 2/20 0.43
▸ RECQL P46063 2/20 0.43
▸ THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15855075 0.81 TTR (0.56) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL6901581 0.78 TTR (0.80) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL31436145 0.78 TTR (0.88) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL598301 0.78 TTR (0.88) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL71021 0.78 TTR (0.88) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL29223890 0.78 CDC25A (0.57) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL30172862 0.77 BACE1 (0.52) TTRKMT2AMEN1MAPTTDP1
SCHEMBL1243588 0.77 BACE1 (0.52) TTRKMT2AMEN1MAPTTDP1
SCHEMBL29223850 0.77 ALDH1A1 (0.42) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL599578 0.75 TTR (0.81) TTRPTPRCKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11215935-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-01-04 — — US disclosed
US-11169455-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2021-11-09 — — US disclosed
US-20200341393-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 — — US disclosed
US-20200341392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 — — US disclosed
US-10754266-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2020-08-25 — — US disclosed
US-20200096884-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO.,LTD. (JP) 2020-03-26 — — US disclosed
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