Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 5/20 | 0.50 |
| ▸ | CDC25B | P30305 | 5/20 | 0.50 |
| ▸ | MAP2K7 | O14733 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP2 | O95551 | 2/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172862 | 1.00 | BACE1 (0.52) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL8559293 | 0.87 | BACE1 (0.45) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL28293793 | 0.83 | MAPT (0.55) | MAPTMAPK1ALDH1A1RAB9ALMNA | |
| 2-Chloropyridine SCHEMBL29209315 | 0.83 | TDP1 (0.46) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL12764551 | 0.82 | HKDC1 (0.54) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL49598 | 0.82 | CDC25A (0.53) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL11264139 | 0.82 | CDC25B (0.48) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL28865505 | 0.82 | CDC25A (0.48) | BACE1MAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL10343653 | 0.80 | TTR (0.43) | MAPTMAPK1ALDH1A1RAB9ALMNA | |
| SCHEMBL7354968 | 0.79 | MAOA (0.50) | MAPTMAPK1ALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869487-A | Metabolic engineering for microbial production of terpenoid products | 马努斯生物合成股份有限公司 | 2020-03-06 | — | — | CN | claimed |
| CN-107389650-A | SERS active-substrate of gold nanoshell probe and its preparation method and application | 东南大学 | 2017-11-24 | — | — | CN | claimed |
| US-20120093917-A1 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2012-04-19 | — | — | US | claimed |
| CN-85106263-A | Heat-staple polymer images and forming method thereof | — | 1987-01-21 | — | — | CN | claimed |
| JP-7070561-A | — | — | None | — | — | JP | disclosed |
| CN-112876929-B | Protective film composition, method for manufacturing semiconductor device, and laser cutting method | 奇美实业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-112876929-A | Protective film composition, method for manufacturing semiconductor device, and laser dicing method | 奇美实业股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-108008600-B | Radiation-sensitive composition | 三菱瓦斯化学株式会社 | 2021-02-09 | — | — | CN | disclosed |
| EP-3115380-B1 | COMPOSITE RESIN COMPOSITION AND SAME RESIN COMPOSITION PRODUCTION METHOD | NAGASE CHEMTEX CORP (JP) | 2021-01-20 | — | — | EP | disclosed |
| CN-107389650-B | SERS active substrate of gold nanoshell probe and preparation method and application thereof | 东南大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-106146338-B | Naphthaquinone derivative containing adamantyl, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-08 | — | — | CN | disclosed |
| CN-110755421-A | Application of isothiocyanate in preparation of glutathione reductase inhibitor | 浙江省肿瘤医院 | 2020-02-07 | — | — | CN | disclosed |
| WO-2009148961-A2 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-10 | — | — | WO | disclosed |
| CN-1827578-A | Anti-tumor naphthoquinone formic acid soft analogues | UNIV SHANGHAI JIAOTONG (CN) | 2006-09-06 | — | — | CN | disclosed |
| EP-0430164-B1 | Process for preparation of 2-substituted-1,4-naphthoquinone | NIPPON CATALYTIC CHEM IND (JP) | 1995-03-22 | — | — | EP | disclosed |
| JP-H0770561-A | CORROSION PREVENTIVE FOR CONCRETE STRUCTURE | KAWASAKI KASEI CHEM LTD | 1995-03-14 | — | — | JP | disclosed |
| US-5329026-A | Oxidation of substituted naphthoquinone, adding a diene compound to reaction product, separation | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0430164-A2 | Process for preparation of 2-substituted-1,4-naphthoquinone | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| EP-0237108-B1 | PROCESS FOR THE PREPARATION OF CARBONYL COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-26 | — | — | EP | disclosed |
| EP-0237108-A1 | Process for the preparation of carbonyl compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093917-A1 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER | RNASE1, DCLRE1B, FEN1 | BACE1 1766/4885MAPT 3716/4885MAPK1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.