Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886954 | 0.77 | KAT2B (0.50) | KAT2BCA1CA2 | |
| SCHEMBL21814475 | 0.77 | TDP1 (0.52) | KAT2BALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL9262493 | 0.76 | MAPT (0.46) | CA12CA9CA1ALDH1A1KMT2A | |
| SCHEMBL21886795 | 0.73 | CA12 (0.49) | KAT2BCA12CA9CA1DDAH1 | |
| SCHEMBL9256085 | 0.73 | PMM2 (0.45) | KAT2BCA12CA9CA1ALDH1A1 | |
| Terephthalic Acid SCHEMBL31588347 | 0.66 | TSHR (0.92) | CA12CA9CA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8506515 | 0.66 | CA12 (0.71) | CA12CA9CA1DDAH1KDM4E | |
| Terephthalic Acid SCHEMBL2511919 | 0.63 | TSHR (1.00) | CA12CA9CA1ALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL175823 | 0.63 | TSHR (1.00) | CA12CA9CA1ALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.63 | TSHR (1.00) | CA12CA9CA1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |