Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530212 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1GAAHTTBLM | |
| SCHEMBL24767734 | 0.83 | FBP1 (0.57) | ATICFBP1POLBNT5E | |
| SCHEMBL21887926 | 0.81 | ATIC (0.50) | ATICFBP1KDM4EALDH1A1GAA | |
| Mizoribine Monophosphate SCHEMBL16329889 | 0.81 | ATIC (0.80) | ATICFBP1KDM4EALDH1A1GAA | |
| Mizoribine Monophosphate SCHEMBL12727826 | 0.81 | ATIC (0.80) | ATICFBP1KDM4EALDH1A1GAA | |
| SCHEMBL29619496 | 0.80 | FBP1 (0.56) | ATICFBP1POLBNT5E | |
| SCHEMBL21888939 | 0.80 | ATIC (0.48) | ATICFBP1KDM4EALDH1A1GAA | |
| SCHEMBL21887947 | 0.78 | TYMS (0.47) | — | |
| SCHEMBL1152822 | 0.77 | ADRB1 (0.71) | POLBNT5E | |
| SCHEMBL20419993 | 0.77 | KDM4E (0.40) | ATICFBP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |