Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | UMPS | P11172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887928 | 0.81 | ATIC (0.40) | ATICFBP1LDHATK1UMPS | |
| SCHEMBL21888941 | 0.78 | LMNA (0.41) | ATICFBP1LDHATK1 | |
| SCHEMBL21887947 | 0.78 | TYMS (0.47) | — | |
| SCHEMBL21888939 | 0.77 | ATIC (0.48) | ATICFBP1LDHA | |
| SCHEMBL24024486 | 0.73 | ATIC (0.62) | ATICFBP1LDHAUMPS | |
| SCHEMBL29687021 | 0.73 | ATIC (0.62) | ATICFBP1LDHAUMPS | |
| SCHEMBL21888254 | 0.73 | PNP (0.40) | ATICFBP1LDHATK1 | |
| SCHEMBL21888121 | 0.70 | LMNA (0.39) | ATICFBP1 | |
| SCHEMBL21887985 | 0.70 | LMNA (0.39) | ATICFBP1 | |
| SCHEMBL21888262 | 0.70 | ATIC (0.43) | ATICFBP1LDHAUMPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |