Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | UMPS | P11172 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888098 | 0.81 | ATIC (0.38) | ATICFBP1UMPSLDHATK1 | |
| SCHEMBL24024486 | 0.76 | ATIC (0.62) | ATICFBP1UMPSLDHADNPH1 | |
| SCHEMBL29687021 | 0.76 | ATIC (0.62) | ATICFBP1UMPSLDHADNPH1 | |
| SCHEMBL21887947 | 0.74 | TYMS (0.47) | — | |
| SCHEMBL21888262 | 0.70 | ATIC (0.43) | ATICFBP1UMPSLDHADNPH1 | |
| SCHEMBL21888048 | 0.68 | LMNA (0.41) | ATICFBP1ADORA1SMN1; SMN2 | |
| SCHEMBL21888051 | 0.68 | LMNA (0.41) | ATICFBP1ADORA1SMN1; SMN2 | |
| SCHEMBL21887950 | 0.68 | LMNA (0.41) | ATICFBP1ADORA1P2RY2SMN1; SMN2 | |
| SCHEMBL4358224 | 0.66 | ATIC (0.55) | ATICFBP1LDHADNPH1PRKAB2 | |
| SCHEMBL21888123 | 0.65 | LMNA (0.39) | ATICFBP1ADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |