Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 20/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21566695 | 0.76 | GRM4 (0.36) | GRM4CYP1A2 | |
| SCHEMBL19287867 | 0.74 | GRM4 (0.41) | GRM4CYP1A2 | |
| SCHEMBL17515573 | 0.73 | GRM4 (0.50) | GRM4 | |
| SCHEMBL24004539 | 0.73 | GRM4 (0.39) | GRM4CYP1A2 | |
| SCHEMBL22927997 | 0.71 | PSMD14 (0.40) | GRM4CYP1A2 | |
| SCHEMBL10066651 | 0.70 | PSMD14 (0.44) | GRM4 | |
| SCHEMBL3889048 | 0.68 | PSMD14 (0.42) | GRM4CYP1A2 | |
| SCHEMBL21888882 | 0.67 | — | — | |
| SCHEMBL19273386 | 0.66 | KCNMA1 (0.41) | GRM4 | |
| SCHEMBL18672882 | 0.63 | MEN1 (0.36) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115388-A1 | IRAK4 MODULATORS | GENENTECH, INC. (US) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115388-A1 | IRAK4 MODULATORS | IRAK4, IRAK1, IRAK2 | GRM4 502/4885CYP1A2 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.