Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19720734 | 1.00 | GABRR1 (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL19720678 | 0.82 | PDK1 (0.43) | TDP1ALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL21889705 | 0.80 | RAB9A (0.47) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL1832187 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL1832185 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL17532549 | 0.79 | TRPV1 (0.41) | TRPV1ALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL30249967 | 0.79 | ALDH1A1 (0.45) | LMNATRPV1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18261067 | 0.79 | TRPV1 (0.41) | TRPV1ALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL13455423 | 0.79 | ALDH1A1 (0.43) | TDP1TRPV1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20240571 | 0.78 | GABRR1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055973-A1 | ESTROGEN RECEPTOR TARGETING ANTAGONISTS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2020-03-19 | — | — | WO | disclosed |