SCHEMBL21889666

SCHEMBL21889666

CCNC(=O)C(=O)c1c(C)c(C(=O)Nc2ccc(F)c(F)c2)n(C)c1C

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 14/20 0.47
TSHR P16473 2/20 0.44
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
BUB1 O43683 1/20 0.42
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19347016 0.93 TSHR (0.44) SLC10A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL21427884 0.91 TSHR (0.49) SLC10A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL19332126 0.89 SLC10A1 (0.45) SLC10A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL19332176 0.89 SLC10A1 (0.47) SLC10A1TSHRMAPTSMN1; SMN2NPC1
SCHEMBL30033987 0.89 SLC10A1 (0.47) SLC10A1TSHRMAPTSMN1; SMN2NPC1
SCHEMBL30035645 0.89 SLC10A1 (0.45) SLC10A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL19347059 0.88 SLC10A1 (0.49) SLC10A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL22545623 0.88 SLC10A1 (0.49) SLC10A1MAPTSMN1; SMN2NPC1POLB
SCHEMBL19332348 0.88 SLC10A1 (0.44) SLC10A1TSHRMAPTSMN1; SMN2LMNA
SCHEMBL21889751 0.87 SLC10A1 (0.45) SLC10A1TSHRMAPTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056135-A1 MONOMER AND MULTIMERIC ANTI-HBV AGENTS EMORY UNIVERSITY (US) 2023-02-23 US disclosed
WO-2020072955-A1 MONOMER AND MULTIMERIC ANTI-HBV AGENTS EMORY UNIVERSITY (US) 2020-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230056135-A1 MONOMER AND MULTIMERIC ANTI-HBV AGENTS HAVCR2, HMBS, HDGF SLC10A1 8/4885TSHR 4386/4885MAPT 2991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.