SCHEMBL21889751

SCHEMBL21889751

Cc1c(C(=O)C(=O)NCCCCO)c(C)n(C)c1C(=O)Nc1ccc(F)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 16/20 0.45
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21889664 0.99 SLC10A1 (0.45) SLC10A1SMN1; SMN2TSHRRECQLNPC1
SCHEMBL21889594 0.91 SLC10A1 (0.44) SLC10A1SMN1; SMN2TSHRRECQL
SCHEMBL21827808 0.89 SLC10A1 (0.42) SLC10A1SMN1; SMN2TSHRRECQLNPC1
SCHEMBL21889660 0.87 SLC10A1 (0.41) SLC10A1SMN1; SMN2TSHRRECQLMAPT
SCHEMBL21889666 0.87 SLC10A1 (0.47) SLC10A1SMN1; SMN2TSHRNPC1POLB
SCHEMBL21843994 0.85 TSHR (0.43) SLC10A1SMN1; SMN2TSHRMAPT
SCHEMBL19332126 0.84 SLC10A1 (0.45) SLC10A1SMN1; SMN2TSHRNPC1POLB
SCHEMBL30035645 0.84 SLC10A1 (0.45) SLC10A1SMN1; SMN2TSHRNPC1POLB
SCHEMBL30033987 0.84 SLC10A1 (0.47) SLC10A1SMN1; SMN2TSHRNPC1POLB
SCHEMBL19332176 0.84 SLC10A1 (0.47) SLC10A1SMN1; SMN2TSHRNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056135-A1 MONOMER AND MULTIMERIC ANTI-HBV AGENTS EMORY UNIVERSITY (US) 2023-02-23 US disclosed
CN-113166115-A Monomeric and multimeric anti-HBV agents 埃默里大学 2021-07-23 CN disclosed
WO-2020072955-A1 MONOMER AND MULTIMERIC ANTI-HBV AGENTS EMORY UNIVERSITY (US) 2020-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230056135-A1 MONOMER AND MULTIMERIC ANTI-HBV AGENTS HAVCR2, HMBS, HDGF SLC10A1 8/4885SMN1; SMN2 4457/4885TSHR 4386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.