SCHEMBL21889682

SCHEMBL21889682

O=C1Oc2ccccc2C1c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G6 O60733 4/20 0.43
MAPK1 P28482 3/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
BLM P54132 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
FAAH O00519 1/20 0.43
NPC1 O15118 1/20 0.43
GMNN O75496 1/20 0.43
LMNA P02545 1/20 0.43
MTOR P42345 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TRPC5 Q9UL62 1/20 0.43
TRPC6 Q9Y210 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668166 0.85 CYP2C9 (0.49) PLA2G6MAPK1MAPTALDH1A1HPGD
SCHEMBL22167524 0.77 CYP1A2 (0.49) ALDH1A1NPSR1NPC1RAB9AKDM1A
SCHEMBL6074814 0.75 CYP2C9 (0.46) MAPTALDH1A1HPGDBLMNPSR1
SCHEMBL501810 0.74 GAA (0.65) MAPK1MAPTALDH1A1HPGDNPSR1
Phosphine SCHEMBL23295992 0.73 GAA (0.63) MAPK1MAPTALDH1A1HPGDNPSR1
SCHEMBL28854437 0.71 POLB (0.42) ALDH1A1HPGDRAB9ASMN1; SMN2KDM4E
SCHEMBL2358320 0.71 MAPT (0.56) MAPK1MAPTALDH1A1HPGDBLM
SCHEMBL29462549 0.71 MAPT (0.56) MAPK1MAPTALDH1A1HPGDBLM
SCHEMBL11269105 0.70 MEN1 (0.40) MAPTALDH1A1NPSR1LMNAKDM4E
SCHEMBL416279 0.70 CYP1A2 (0.53) ALDH1A1NPSR1NPC1RAB9AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230157720-A1 ENDOSCOPIC FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND ENDOSCOPIC-FLEXIBLE-TUBE-BASE-COVERING MATERIAL FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-11540702-B2 Flexible tube for endoscope, endoscopic medical device, resin composition for covering flexible tube substrate for endoscope, and set of resin compositions for covering flexible tube substrate for endoscope FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
US-20200107697-A1 FLEXIBLE TUBE FOR ENDOSCOPE, ENDOSCOPIC MEDICAL DEVICE, RESIN COMPOSITION FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE, AND SET OF RESIN COMPOSITIONS FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed