SCHEMBL668166

SCHEMBL668166

c1ccc2c(c1)Oc1ccccc1C2c1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.49
KDM1A O60341 1/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
ATM Q13315 2/20 0.44
SLC6A4 P31645 4/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A3 Q01959 2/20 0.42
NISCH Q9Y2I1 1/20 0.41
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
MAPK1 P28482 3/20 0.40
BLM P54132 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
KEAP1 Q14145 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22167524 0.86 CYP1A2 (0.49) KDM1AMAOAMAOBALDH1A1NPSR1
SCHEMBL21889682 0.85 PLA2G6 (0.43) CYP2C9KDM1AATMSLC6A4SLC6A2
SCHEMBL416279 0.79 CYP1A2 (0.53) CYP2C9KDM1AALDH1A1NPSR1NPC1
SCHEMBL6675754 0.77 KDM1A (0.53) KDM1ASLC6A4SLC6A2SLC6A3KDM4E
SCHEMBL3558507 0.74 NQO1 (0.45) CYP2C9MAOAMAOBATMNISCH
SCHEMBL2736398 0.72 MAOA (0.52) CYP2C9MAOAMAOBATMNISCH
SCHEMBL22167529 0.72 CYP1A2 (0.46) KDM1AALDH1A1NPSR1MEN1KMT2A
SCHEMBL21662347 0.72 MEN1 (0.45) KDM1AALDH1A1HPGDNPSR1EPHX1
SCHEMBL22167530 0.72 CYP1A2 (0.36) CYP2C9MAOAMAOBATMNISCH
SCHEMBL8622033 0.72 HTR2C (0.53) CYP2C9MAOAMAOBATMSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4083174-B1 REFRIGERATION CYCLE DEVICE, REFRIGERATION MACHINE OIL AND REFRIGERANT LEAKAGE PREVENTION AGENT DAIKIN IND LTD (JP) 2025-01-22 EP claimed
CN-117343037-B Spirofluorene naphthoxanthene organic blue light material and preparation method and application thereof 山东浩华新材料科技有限公司 2024-12-03 CN claimed
WO-2024199766-A1 ABSORPTION INCREASE, EFFICIENCY ENHANCEMENT AND SPATIAL LIGHT MODULATION BY MICRO-STRUCTURING COLOR CONVERSION LAYERS SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2024-10-03 WO claimed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP claimed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP claimed
CN-117343037-A Spirofluorene naphthoxanthene organic blue light material and preparation method and application thereof 山东浩华新材料科技有限公司 2024-01-05 CN claimed
EP-4074807-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN The Chemours Company FC, LLC (US) 2022-10-19 EP claimed
EP-1985680-B2 Composition comprising a HFC-1234ze isomer CHEMOURS CO FC LLC (US) 2022-06-29 EP claimed
US-20210355360-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-11-18 US claimed
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-07-08 US claimed
US-20050156138-A1 1,1,1,3,3-Pentafluorobutane refrigerant compositions comprising fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US claimed
US-20050156135-A1 Refrigerant compositions comprising 1-ethoxy-1,1,2,2,3,4,4,4-nonafluorobutane and a hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US claimed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050151111-A1 1,1,1,3,3-Pentafluorobutane refrigerant or heat transfer fluid compositions comprising hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US claimed
WO-2005049761-A1 REFRIGERANT COMPOSITIONS COMPRISING UV FLUORESCENT DYE AND SOLUBILIZING AGENT E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-06-02 WO claimed
US-4758366-A Polyhalogenated hydrocarbon refrigerants and refrigerant oils colored with fluorescent dyes and method for their use as leak detectors WIDGER CHEMICAL CORPORATION (US) 1988-07-19 US claimed
US-3966638-A POLYMERIZATION CATALYST HARGIS IVAN GLEN 1976-06-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355360-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 CYP2C9 1745/4885KDM1A 4753/4885MAOA 2077/4885
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 CYP2C9 1745/4885KDM1A 4753/4885MAOA 2077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.