SCHEMBL2358320

SCHEMBL2358320

O=C1c2ccccc2C(=O)C1c1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
ALDH1A1 P00352 5/20 0.56
RAB9A P51151 5/20 0.56
NPC1 O15118 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
TP53 P04637 4/20 0.54
PTK2B Q14289 1/20 0.54
MAPK1 P28482 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
TDP2 O95551 1/20 0.51
ALOX12 P18054 1/20 0.51
CASP3 P42574 1/20 0.51
HTT P42858 1/20 0.51
GALK1 P51570 1/20 0.51
BLM P54132 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
SENP8 Q96LD8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462549 1.00 MAPT (0.56) MAPTALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL6675754 0.81 KDM1A (0.53) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL6380847 0.73 IDO1 (0.54) MAPTALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL16481156 0.72 KDM1A (0.48) MAPTALDH1A1MAPK1HPGDKDM4E
SCHEMBL12024217 0.72 KDM1A (0.44) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL27962679 0.72 KDM1A (0.44) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL9764610 0.72 ALDH1A1 (0.58) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11807332 0.71 KMT2A (0.53) MAPTALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL11807034 0.71 KMT2A (0.53) MAPTALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL11811509 0.71 RAB9A (0.53) MAPTALDH1A1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3407717-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-07-28 EP claimed
CN-108697091-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2021-07-23 CN claimed
EP-3407716-B9 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2021-07-14 EP claimed
EP-3407720-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-03-10 EP claimed
EP-3408263-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-03-03 EP claimed
EP-3407716-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-02-17 EP claimed
EP-3407718-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-02-17 EP claimed
EP-3232788-B1 TRIAZOLES DERIVATIVES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-06-12 EP claimed
US-20260049039-A1 MICROFIBRILLATED CELLULOSE AS RHEOLOGY MODIFIER IN HIGH IONIC STRENGTH AGRICULTURAL FORMULATIONS AMVAC CHEMICAL CORP (US) 2026-02-19 US disclosed
US-12378165-B2 Pesticide formulation comprising MFC as rheology modifier AMVAC CHEMICAL CORPORATION (US) 2025-08-05 US disclosed
US-20250128993-A1 AGRICULTURAL ADJUVANT COMPRISING MICROFIBRILLATED CELLULOSE AMVAC CHEMICAL CORPORATION 2025-04-24 US disclosed
US-12049431-B2 Agricultural adjuvant comprising microfibrillated cellulose AMVAC Chemical Corporation (Subsidiary of American Vanguard Corporation) (US) 2024-07-30 US disclosed
EP-4380935-A1 POLYMORPHS HAVING PESTICIDAL ACTIVITY Corteva Agriscience LLC (US) 2024-06-12 EP disclosed
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
WO-2016168058-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-10-20 WO disclosed
WO-2016099929-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-06-23 WO disclosed
US-20140271932-A1 RODENTICIDAL COMPOSITION AND METHOD PIC CORPORATION 2014-09-18 US disclosed
WO-2013068785-A1 INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS ACTELION PHARMACEUTICALS LTD (CH) 2013-05-16 WO disclosed
WO-2011094219-A1 VESICULAR FORMULATIONS KROON HENDRICK-ANDRE (US) 2011-08-04 WO disclosed
US-4011332-A RODENTICIDE BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049039-A1 MICROFIBRILLATED CELLULOSE AS RHEOLOGY MODIFIER IN HIGH IONIC STRENGTH AGRICULTURAL FORMULATIONS FIBP, GHDC, MASTL MAPT 2091/4885ALDH1A1 4742/4885RAB9A 3794/4885
US-12378165-B2 Pesticide formulation comprising MFC as rheology modifier MFAP1, PFAS, DDT MAPT 835/4885ALDH1A1 2450/4885RAB9A 1439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.