SCHEMBL21889686

SCHEMBL21889686

Cc1cccc2c1OC(=O)C2c1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
ALDH1A1 P00352 3/20 0.35
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NR3C2 P08235 3/20 0.33
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HPGD P15428 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2614948 0.86 GAA (0.53) GAAALDH1A1CYP3A4MEN1KMT2A
SCHEMBL25723567 0.85 GAA (0.48) GAAALDH1A1ESR1ESR2CYP3A4
SCHEMBL25723554 0.84 ALDH1A1 (0.33) GAAALDH1A1HPGDHTR2AHTR2C
SCHEMBL21889683 0.82 GAA (0.48) GAAALDH1A1MEN1KMT2AKDM4E
SCHEMBL2612450 0.80 GAA (0.50) GAAALDH1A1CYP3A4MEN1KMT2A
SCHEMBL25723546 0.77 HPGD (0.41) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL25723549 0.76 GAA (0.39) GAAMEN1KMT2AMAPTHPGD
SCHEMBL11987177 0.75 GAA (0.59) GAAALDH1A1MAPTHSD17B10HPGD
SCHEMBL824537 0.74 GAA (0.44) GAAALDH1A1ESR1ESR2CYP3A4
SCHEMBL25723561 0.73 GAA (0.49) GAAALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230157720-A1 ENDOSCOPIC FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND ENDOSCOPIC-FLEXIBLE-TUBE-BASE-COVERING MATERIAL FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-20230157720-A1 ENDOSCOPIC FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND ENDOSCOPIC-FLEXIBLE-TUBE-BASE-COVERING MATERIAL FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-11540702-B2 Flexible tube for endoscope, endoscopic medical device, resin composition for covering flexible tube substrate for endoscope, and set of resin compositions for covering flexible tube substrate for endoscope FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
US-20200107697-A1 FLEXIBLE TUBE FOR ENDOSCOPE, ENDOSCOPIC MEDICAL DEVICE, RESIN COMPOSITION FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE, AND SET OF RESIN COMPOSITIONS FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed