Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889693 | 0.77 | NOX1 (0.41) | ALOX5MEN1CYP1A2BCHEPOLB | |
| SCHEMBL21889688 | 0.77 | AHR (0.46) | ALOX5MAOA | |
| Phenoxathiine SCHEMBL7922 | 0.77 | MAOA (0.42) | ATMALOX5MEN1CYP1A2BCHE | |
| Phenoxathiine SCHEMBL29396568 | 0.77 | MAOA (0.42) | ATMALOX5MEN1CYP1A2BCHE | |
| Phenoxathiine SCHEMBL29373698 | 0.77 | MAOA (0.42) | ATMALOX5MEN1CYP1A2BCHE | |
| Phenoxathiine SCHEMBL5699627 | 0.74 | MAOA (0.40) | ATMALOX5MEN1CYP1A2BCHE | |
| Phenoxathiine SCHEMBL10512948 | 0.74 | MAOA (0.40) | ATMALOX5MEN1CYP1A2BCHE | |
| Phenoxathiine SCHEMBL5970725 | 0.74 | MAOA (0.40) | ATMALOX5MEN1CYP1A2BCHE | |
| SCHEMBL19205828 | 0.74 | AHR (0.41) | ATMALOX5MEN1CYP1A2BCHE | |
| SCHEMBL9507670 | 0.73 | LMNA (0.39) | ATMMEN1BCHEMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590239-B2 | Polymer including Troger'S base and isatin moieties and having intrinsic microporosity | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-03-17 | — | — | US | disclosed |