Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 5/20 | 0.35 |
| ▸ | CDK13 | Q14004 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 2/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889962 | 0.88 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL19442310 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL15600841 | 0.80 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL19669736 | 0.78 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL16665574 | 0.74 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL21889706 | 0.74 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL27451925 | 0.74 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL27451922 | 0.74 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL14079971 | 0.74 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2CDK7CDK13 | |
| SCHEMBL21889707 | 0.72 | CHRNB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055973-A1 | ESTROGEN RECEPTOR TARGETING ANTAGONISTS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2020-03-19 | — | — | WO | disclosed |